Two months after the events of "The Change Constant", Sheldon and Leonard repair Sheldon's DNA molecule model as everyone prepares to fly to Sweden for the Nobel Prize award ceremony. Howard and Bernadette nervously leave their kids for the first time with Stuart and Denise, while Raj leaves his dog with Bert. Penny has become pregnant, though she and Leonard are keeping it a secret. On the flight, Raj thinks he spots Sarah Michelle Gellar. Penny's frequent bathroom trips make Sheldon fear she is sick. Leonard reveals the pregnancy to Sheldon, but instead of being excited for Penny, Sheldon is only selfishly relieved that he will not get sick and he exposes the pregnancy, offending Leonard. At the hotel, a series of minor incidents with their kids make Howard and Bernadette want to go home. Much to their dismay, Sheldon is still insensitive. Amy furiously tells Sheldon he broke their friends' hearts and they only tolerate him because he does not intentionally do so, which she also sometimes does. Everyone decides to stay for the ceremony and Raj brings Gellar. After they are awarded their medals, Amy encourages girls to pursue science while Sheldon thanks his family and then individually acknowledges each of his friends and Amy as his other family who always support him. The episode closes with the gang eating in Apartment 4A (an allusion to the final scene in the opening credits) as an acoustic version of the theme song's chorus plays.
Sheldon cannot find the perfect wedding date and begins talking in his sleep, adopting the persona of a laid-back person who goes with the flow. Amy and Penny believe that his subconscious mind is trying to tell him to be more relaxed; his attempt to be so while wearing flip-flops ends in disaster. He decides to leave all the wedding planning to Amy while he wears a Star Trek uniform underneath his tuxedo. Meanwhile, Raj and Stuart both become interested in Bernadette's new coworker Ruchi. While she likes them both as friends, she does not want a relationship with anyone.
It was really hard to pick the right pic for this post, so here is a shot of us in a hug after we filmed the last group scene we would ever film for the series... and TONIGHT is THE NIGHT... it’s the series finale at 8pm EST and then there’s the Young Sheldon (season!) finale, and then a special behind the scenes show hosted by @kaleycuoco and @sanctionedjohnnygalecki and then the entire cast is on @colbertlateshow I hope you get a chance to tune in and i hope you enjoy all of it. If you enjoy it even half as much as we’ve enjoyed (LOVED) creating this show for the past 12 years, then that’ll be a WHOLE WHOLE lot of enjoyment. All of us will miss seeing you in this format, but we will be around in all sorts of ways, I assure you... love love love ❤️❤️❤️
Sheldon's mother Mary refuses to attend his wedding unless he invites his older brother George, with whom he is no longer speaking. Sheldon and Leonard fly to Texas to talk to George, who now owns a chain of tire stores. He refuses to attend and later explains to Leonard and Sheldon that the family sacrificed a lot to fund Sheldon's education, and he was stuck caring for their mother and sister Missy after their father died while Sheldon was in college. Sheldon never thanked him for this. Leonard takes George back to the hotel room where Sheldon apologizes for what he did and the brothers reconcile. George agrees to attend the wedding. Meanwhile, Howard and Bernadette's children contract pinkeye, infecting everyone except Penny, much to Amy's fury. 

Two physicists from Chicago, Dr. Campbell and Dr. Pemberton, accidentally prove Sheldon and Amy's super-asymmetry theory. This puts them on track for a Nobel Prize, but Leonard points out they tend to go to the experimental scientists who prove a concept instead of theorists like Sheldon who come up with it. Meeting with them, they tell Sheldon they are willing to share the Prize but only three names can be on the submission, and they want to cut Amy out. Amy does not want to prevent Sheldon's lifelong dream, but he goes to President Seibert who agrees to fight for Amy on their behalf. Meanwhile, Bernadette's drug has been approved and she wants to promote Penny to lead the marketing team. Penny resists, knowing Bernadette's attitude at work and doubting her own inexperience to take the responsibility, but Bernadette uses reverse-psychology to get Penny to take the job. Penny mirrors Bernadette's commanding style to get the other employees in line, impressing Bernadette.
As the theme of the show revolves around science, many distinguished and high-profile scientists have appeared as guest stars on the show. Famous astrophysicist and Nobel laureate George Smoot had a cameo appearance in the second season.[56] Theoretical physicist Brian Greene appeared in the fourth season, as well as astrophysicist, science populizer, and physics outreach specialist Neil deGrasse Tyson, who also appeared in the twelfth season.
Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for string theory rather than loop quantum gravity.[70] When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard, and Penny asking Sheldon to teach her physics.[71] Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior.[72] 

Initial reception for the series was mixed. The review aggregation website Rotten Tomatoes reported a 52% approval rating for the first season based on reviews from 23 critics, with an average rating of 5.18/10. The website's critical consensus reads, "The Big Bang Theory brings a new class of character to mainstream television, but much of the comedy feels formulaic and stiff."[91] On Metacritic, the season holds a score of 57 out of 100, based on reviews from 23 critics, indicating "mixed or average reviews".[92] Later seasons received more acclaim and in 2013, TV Guide ranked the series #52 on its list of the 60 Best Series of All Time.[93]
Kunal Nayyar as Rajesh Koothrappali:[46] A particle astrophysicist originally from New Delhi, India. Raj is initially unable to talk to women unless he drinks alcohol. Raj also has very feminine tastes and often takes on a stereotypical female role in his friendship with Howard as well as in the group of four men. Raj later dates Lucy (Kate Micucci), who also suffers from social anxiety, but it eventually ends; he later speaks to Penny without alcohol and thus overcomes his selective mutism. He begins dating Emily and their relationship later becomes exclusive. Raj also has a Yorkshire Terrier named Cinnamon.
Leonard Hofstadter and Sheldon Cooper are both brilliant physicists working at Cal Tech in Pasadena, California. They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways. They are also friends with their Cal Tech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali. The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books. As they are self-professed nerds, all have little or no luck with women. When Penny, a pretty woman and an aspiring actress from Omaha, moves into the apartment across the hall from Leonard and Sheldon's, Leonard has another aspiration in life, namely to get Penny to be his girlfriend. Written by Huggo
Campbell and Pemberton start a publicity tour for their Nobel campaign, including appearing on The Ellen DeGeneres Show. Caltech reaches out to previous winners, including George Smoot, Kip Thorne and Frances H. Arnold, only to find that Sheldon has offended most of them in the past. Leonard and Penny convince them to show up to the reception, only for Pemberton and Campbell to crash the party. Leonard holds Sheldon back, only for Amy to verbally snap at them. Meanwhile, with Halley scared of the dark, Stuart and Bernadette turn Howard's story from his time in outer space into the children's book: The Frightened Little Astronaut. Howard is embarrassed until Bernadette talks him into helping children and Stuart's art career by letting it be published.
Categories: The Big Bang Theory2007 American television series debuts2000s American college television series2000s American romantic comedy television series2000s American sitcoms2010s American college television series2010s American romantic comedy television series2010s American sitcoms2019 American television series endingsCBS network showsCultural depictions of scientistsEnglish-language television programsNerd culturePhysics in fictionPrimetime Emmy Award-winning television seriesTelevision series about friendshipTelevision series by Warner Bros. TelevisionTelevision series created by Bill PradyTelevision series created by Chuck LorreTelevision shows featuring audio descriptionTelevision shows set in Pasadena, California
The fourth season's second half began on June 30, 2011. Season 5 began airing on November 3, 2011, at 8:00 p.m. as part of E4's Comedy Thursdays, acting as a lead-in to the channel's newest comedy, Perfect Couples. Episode 19, the highest-viewed episode of the season, attracted 1.4 million viewers.[145] Season 6 premiered on November 15, 2012, with 1.89 million viewers and a further 469,000 on the time shift channel, bringing the total to 2.31 million, E4's highest viewing ratings of 2012, and the highest the channel had received since June 2011. The sixth season returned in mid-2013 to finish airing the remaining episodes.[146] Season 7 premiered on E4 on October 31, 2013 at 8:30pm and hit multiple ratings records this season. The second half of season seven aired in mid 2014.[147] The eighth season premiered on E4 on October 23, 2014 at 8:30 p.m.[148] During its eighth season, The Big Bang Theory shared its 8:30 p.m. time period with fellow CBS comedy, 2 Broke Girls. Following the airing of the first eight episodes of that show's fourth season, The Big Bang Theory returned to finish airing its eighth season on March 19, 2015.[149]
Melissa Rauch as Bernadette Rostenkowski-Wolowitz (recurring season 3, starring seasons 4–12):[51] A young woman who initially is a co-worker at The Cheesecake Factory with Penny to pay her way through graduate school, where she is studying microbiology. Bernadette is introduced to Howard by Penny; at first, they do not get along, apparently having nothing in common. They date and later get engaged and married. Although generally a sweet and good-natured person, Bernadette has a short fuse and can be vindictive and lash out when provoked.

Categories: The Big Bang Theory2007 American television series debuts2000s American college television series2000s American romantic comedy television series2000s American sitcoms2010s American college television series2010s American romantic comedy television series2010s American sitcoms2019 American television series endingsCBS network showsCultural depictions of scientistsEnglish-language television programsNerd culturePhysics in fictionPrimetime Emmy Award-winning television seriesTelevision series about friendshipTelevision series by Warner Bros. TelevisionTelevision series created by Bill PradyTelevision series created by Chuck LorreTelevision shows featuring audio descriptionTelevision shows set in Pasadena, California
Keith Carradine has appeared in three episode as Penny's father, Wyatt, first in Season 4. Katey Sagal, who played the on-screen mother of Kaley Cuoco's character in the 2002-2005 sitcom 8 Simple Rules, has appeared as Penny's mother in one episode of The Big Bang Theory. Jack McBrayer has appeared in one episode of The Big Bang Theory as Penny's brother, Randall.
Sheldon's childhood friend from Texas, Tam, is visiting the university with his son. Sheldon does not want to see him and the others wonder why Sheldon has never mentioned Tam. Tam is unaware Sheldon is angry with him, thinking they just naturally drifted apart. Sheldon's brother George does not know the reason either. Sheldon eventually reveals Tam promised he would move to California with Sheldon, but then got a girlfriend and stayed with her, leaving Sheldon feeling abandoned. Tam and Sheldon make up and Sheldon has Leonard take Tam to the airport. Meanwhile, Penny and Bernadette want to get to know Anu, impressed by her connections in the hotel industry. They tell her embarrassing things about Raj and wonder if they can go out with her again after Raj confronts them. 
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